Epitope peptides of influenza H3N2 virus neuraminidase gene designed by immunoinformatics
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منابع مشابه
Epitope peptides of influenza H3N2 virus neuraminidase gene designed by immunoinformatics.
The virus surface protein neuraminidase (NA) is a main subtype-specific antigen in influenza type A viruses. Neuraminidase functions as an enzyme to break the bonds between hemagglutinin (HA) and sialic acid to release newly formed viruses from infected cells. In this study, NA genes from the H3N2 subtype virus were sequenced and NA proteins were screened for B-cell epitopes and assessed based ...
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Antiserum specific for influenza A2 neuraminidase was produced by immunization of rabbits with the purified enzyme which had been isolated by electrophoresis from the proteins of a detergent-disrupted AoA2 influenza virus recombinant [X-7 (Fl)]. This recombinant contained hemagglutinin of the Ao subtype and A2 neuraminidase. Antiserum to the isolated A2 neuraminidase did not react in any of fou...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2011
ISSN: 1672-9145,1745-7270
DOI: 10.1093/abbs/gmr101